Old Human Capital Priorities profile — do I need to do anything now that it's closed?

Since all 8 old streams closed on the same date the new stream launched, an old profile with no nomination yet generally does not carry forward into the new Workforce Priority stream, you'd need a new job offer meeting the new stream's criteria and a fresh Expression of Interest once it opens. If you already had an actual nomination (not just a profile) before the close date, that's a different situation, confirm directly with OINP rather than assuming either way. General information from my own experience, not legal advice — for anything specific to your file, a licensed RCIC or immigration lawyer can look at your actual documents.